Militants also attacked reinforcements sent to the base on Tuesday morning, killing three soldiers and wounding 10, according to a provisional tally.
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Mali has been struggling to contain a jihadist insurgency that first emerged in the north of the country in 2012, and which has since spread to the center of the country and neighboring Burkina Faso and Niger.
Thousands of soldiers and civilians have been killed in the fighting to date, and hundreds of thousands of people have been forced to flee their homes.
In Mali, the center of the vast country has become the epicenter of the violence, with jihadist attacks and ethnic violence commonplace.
Anger at the brutal conflict contributed to protests against President Ibrahim Boubacar Keita this year, which culminated in his ouster in a military coup on August 18.
THE GUARDIAN